Some Vietnam vets currently have PTSD 40 years after war ended, study finds

The study by Charles R. Marmar, M.D., of the New York University Langone Medical Center, and colleagues builds on the National Vietnam Veterans Readjustment Study (NVVRS), which was implemented from 1984 through 1988 (about 10 years after the war ended). The authors' National Vietnam Veterans Longitudinal Study (NVVLS) is the first follow-up to NVVRS. There were 1,839 veterans from the original study still living at the time of the NVVLS from July 2012 to May 2013 and 78.8 percent (n=1,450) of the veterans participated in at least one phase of the study.

The authors estimate a prevalence among male war zone veterans of 4.5 percent for a current PTSD diagnosis based on the Clinician-Administered PTSD Scale for DSM-5; 10.8 percent based on that assessment plus subthreshold PTSD; and 11.2 percent based on the PTSD Checklist for DSM-5 items for current war-zone PTSD. Among female veterans, the estimates were 6.1 percent, 8.7 percent and 6.6 percent, respectively.

The study also found coexisting major depression in 36.7 percent of veterans with current war-zone PTSD.

About 16 percent of war zone Vietnam veterans reported an increase of more than 20 points on a PTSD symptom scale while 7.6 percent reported a decrease of greater than 20 points on the symptom scale. "An important minority of Vietnam veterans are symptomatic after four decades, with more than twice as many deteriorating as improving," the study notes.

The authors conclude: "Policy implications include the need for greater access to evidence-based mental health services; the importance of integrating mental health treatment into primary care in light of the nearly 20 percent mortality; attention to the stresses of aging, including retirement, chronic illness, declining social support and cognitive changes that create difficulties with the management of unwanted memories; and anticipating challenges that lie ahead for Iraq and Afghanistan veterans," the study concludes.

Editorial: Measuring the Long-Term Impact of War Zone Military Service

In a related editorial, Charles W. Hoge, M.D., of the Walter Reed Army Institute of Research, Silver Spring, Md., writes: "This methodologically superb follow-up of the original NVVRS cohort offers a unique window into the psychiatric health of these veterans 40 years after the war's end. No other study has achieved this quality of longitudinal information, and the sobering findings tell us as much about the Vietnam generation as about the lifelong impact of combat service in general, relevant to all generations."