Adverse childhood experiences linked to frequent headache in adults

Using data from the Adverse Childhood Experiences (ACE) Study of 17,337 adult members of the Kaiser Health Plan in San Diego, Gretchen E. Tietjen, MD, of the University of Toledo College Of Medicine, and her team found that the number of ACEs showed a graded relationship to the likelihood of experiencing frequent headaches. Her study was supported by the Centers for Disease Control and Prevention.

"We looked at eight ACEs -- emotional, physical, or sexual abuse, witnessing domestic violence, growing up with mental illness in the home, having household members who were incarcerated or were abusing drugs, and experiencing parental separation or divorce,." said Dr. Tietjen. "Each ACE increased the chance of frequent headache, and as the number of ACEs increased, so did the risk of frequent headache. This 'dose-response' relationship' suggests that ACEs may contribute to the development and frequency of severe headaches later in life."

"Earlier studies have linked childhood maltreatment to frequent headaches and migraine," said David Dodick, M.D., president of the AHS. "The biological underpinnings of this relationship should be a target of future research and clinicians should be aware of and evaluate for this important relationship in order to facilitate appropriate management strategies"