After a fight with a partner, brain activity predicts emotional resiliency

Individuals who show more neural activity in the lateral prefrontal cortex are less likely to be upset the day after fighting with partners, according to a study in this month's Biological Psychiatry. The findings point to the lateral prefrontal cortex's role in emotion regulation, and suggest that improved function within this region may also improve day-to-day mood.

"What we found, as you might expect, was that everybody felt badly on the day of the conflict with their partners," says lead author Christine Hooker, assistant professor of psychology in Harvard's Faculty of Arts and Sciences. "But the day after, people who had high lateral prefrontal cortex activity felt better and the people who had low lateral prefrontal cortex activity continued to feel badly."

Hooker's co-authors are Özlem Ayduk, Anett Gyurak, Sara Verosky, and Asako Miyakawa, all of the University of California at Berkeley.

Research has previously shown that the lateral prefrontal cortex is associated with emotion regulation in laboratory tests, but the effect has never been proven to be connected to experiences in day-to-day life.

This study involved healthy couples in a relationship for longer than three months. While in an fMRI scanner, participants viewed pictures of their partners with positive, negative, or neutral facial expressions and their neural activity was recorded while reacting to the images. While in the lab, participants were also tested for their broader cognitive control skills, such as their ability to control impulses and the shift and focus of attention.

For three weeks, the couples also recorded in an online diary their daily emotional state and whether they had had a fight with their partners.

Hooker found that participants who displayed greater activity in their lateral prefrontal cortex while viewing their partners' negative facial expressions in the scanner were less likely to report a negative mood the day after a fight with their partners, indicating that they were better able to emotionally "bounce back" after the conflict.

She also found that those who had more activity in the lateral prefrontal cortex and greater emotional regulation after a fight displayed more cognitive control in laboratory tests, indicating a link between emotion regulation and broader cognitive control skills.

"The key factor is that the brain activity in the scanner predicted their experience in life," says Hooker. "Scientists believe that what we are looking at in the scanner has relevance to daily life, but obviously we don't live our lives in a scanner. If we can connect what we see in the scanner to somebody's day-to-day emotion-regulation capacity, it could help psychologists predict how well people will respond to stressful events in their lives."

While Hooker acknowledges that more work must be done to develop clinical applications for the research, it may be that lateral prefrontal cortex function provides information about a person's vulnerability to develop mood problems after a stressful event. This raises the question as to whether increasing lateral prefrontal cortex function will improve emotion regulation capacity.

The research was funded by the National Institute for Mental Health and the National Alliance for Research in Schizophrenia and Depression.