Effects of spinach extract on satiety: Feel full, curb cravings

The study examines the effect of consuming a single dose of concentrated extract of thylakoids from spinach on satiety, food intake, lipids, and glucose compared to a placebo. Sixty people (30 males and 30 females) classified as overweight or obese took part in a double-blind randomized crossover study. They consumed either the spinach extract or a placebo in random order at least a week apart. Using blood samples, their lipid and glucose levels were measured before a normal breakfast, followed by a dose of the extract and standard lunch four hours later. After another four hours, pizza was served, and throughout the interval, various blood tests and responses were gathered.

The results showed that the spinach extract containing thylakoids increased satiety over a two-hour period compared to a placebo. There were no differences in plasma lipids and energy intake at dinner, but males showed a trend toward decreased energy intake. Thylakoid consumption may influence gender-specific food cravings -- in a previous study, it was found that in women, a reduced urge for sweets was significant after a single dose of the spinach extract and the reduced urge for sweets was sustained throughout the study.

Article co-author, Frank L. Greenway MD, summarizes: "The reduction in hunger and the desire for salty food that we saw in this study might make thylakoids particularly useful for people with high blood pressure and associated weight problems."