Coming Epidemic Of Type 2 Diabetes In Young Adults

In a new article, University of Michigan C.S. Mott Children’s Hospital pediatric endocrinologist Joyce Lee, M.D., M.P.H, warns that the most damaging effects of childhood obesity have yet to surface, and will likely result in an epidemic of type 2 diabetes among young adults, leading to a greater number of diabetes complications, and ultimately, lower life expectancy.

“The full impact of the childhood obesity epidemic has yet to be seen because it can take up to 10 years or longer for obese individuals to develop type 2 diabetes,” says Lee, a member of the Child Health Evaluation and Research (CHEAR) Unit at Mott. “Children who are obese today are more likely to develop type 2 diabetes as young adults.”

The longer a person has diabetes, Lee says, the more likely he or she is to develop devastating complications. Young adults with type 2 diabetes are therefore more likely to develop complications such as blindness and kidney failure during their lifetimes, and they have higher rates of diabetes complications and heart disease than older adults with type 2 diabetes.

Plus, babies born to young women with type 2 diabetes are at greater risk for obesity and type 2 diabetes, creating a vicious cycle.

“Recent studies suggest that there have been dramatic increases in type 2 diabetes among individuals in their 20s and 30s, whereas it used to be that individuals developed type 2 diabetes in their late 50s or 60s, “ notes Lee, assistant professor in the Department of Pediatrics and Communicable Diseases at the U-M Medical School. “This may be the first indication of a type 2 diabetes epidemic among young adults who were obese during childhood.”

Given the delayed negative effects of childhood obesity, Lee says that there needs to be a greater overall investment in childhood obesity, to prevent development of type 2 diabetes.

“Our society heavily invests in the treatment and management of chronic diseases like type 2 diabetes for adults. But it spends very little for the prevention and treatment of childhood obesity to stave off the onset of type 2 diabetes,” says Lee.

“If there isn’t a significant investment in obesity prevention and treatment during childhood within schools, communities, and the health care system, recent trends in childhood obesity will likely lead to increases in type 2 diabetes among young adults, resulting in even greater costs to society and the health care system.”

Lee notes that further studies are needed to learn more about how trends in childhood obesity will impact future rates and age at onset of type 2 diabetes.

These studies will help assess the future burden of disease and disability in the population, and to evaluate whether interventions in childhood can successfully prevent individuals from developing type 2 diabetes over their lifetimes.

Funding: Lee’s work on this study was supported by the U-M Clinical Sciences Scholars Program.

Reference: Archives of Pediatric & Adolescent Medicine, July 2008, Vol. 162, No. 7.