Physicists Turn Single Molecules Into Working Transistors

They have applied for a patent on their device, called Quantum Interference Effect Transistor, nicknamed "QuIET." The American Chemical Society publication, "Nano Letters," has published the researchers' article about it online at Nano Letters. The research is planned as the cover feature in the print edition in November.

A transistor is a device that switches electrical current on and off, just like a valve turns water on and off in a garden hose. Industry now uses transistors as small as 65 nanometers. The UA physicists propose making transistors as small as a single nanometer, or one billionth of a meter.

"All transistors in current technology, and almost all proposed transistors, regulate current flow by raising and lowering an energy barrier," University of Arizona physicist Charles A. Stafford said. "Using electricity to raise and lower energy barriers has worked for a century of switches, but that approach is about to hit the wall."

Transistors can't shrink much smaller than 25 nanometers, or 1/40,000 the width of a pinhead, because scaling down further creates intractable energy problems, Stafford said. Even if it were possible to build an ultra-advanced laptop computer with molecule-sized transistors using current transistor technology, it would take a city's worth of electricity to run the laptop, and the thing would get so hot it would probably vaporize.

Stafford, UA physicist Sumit Mazumdar and David Cardamone, who received his doctorate from UA in 2005, began thinking about the problem of next-generation transistor technology three years ago. They realized that quantum mechanics can solve the problem of how to regulate current flow in a single-molecule transistor that would work at room temperature.

"Our approach is a little more finesse than brute force," Cardamone said. "We don't put up a wall to stop current. It's just that we can regulate how electron waves combine to turn the transistor on or off."

The simplest molecule they propose for a transistor is benzene, a ring-like molecule. They propose attaching two electrical leads to the ring to create two alternate paths through which current can flow.

They also propose attaching a third lead opposite one of the electrical leads. Other researchers have succeeded in attaching two contacts to a molecule this small, but attaching the third is the trick -- and the point. The third lead is what turns the device on and off, the "valve."

"In classical physics, the two currents through each arm of the ring would just add," Stafford said. "But quantum mechanically, the two electron waves interfere with each other destructively, so no current gets through. That's the 'off' state of the transistor."

The transistor is turned on by changing the phase of the waves so they don't destructively interfere with each other, opening up addiitonal paths through the third lead.

"It took a while to go from the idea of how this could work to developing realistic calculations of this kind of system," Stafford said. "We were able to do the simplest kind of quantum chemical calculations which neglect interactions between different electrons within a few weeks. But it took some time to put in all the electron interactions that demonstrate this really is a very robust device."

According to the Semiconductor Research Corp. it typically takes a dozen years for a new idea to go from initial scientific publication to commercial technological application, Stafford noted.

"That means if the computer industry is to continue its recent pace in making smaller-scale computers, we should have had this idea yesterday, " Cardamone said.

Why all this effort to make incomprehensibly small computers? Why expend so much brainpower on nanocomputing?

More computing power will result in more realistic simulations, whether you're a scientist modeling global warming or supernovae explosions, or an entertainment industry animator creating believable emotion in a simulated human face, Stafford said.

Nanocomputers could have a major impact in medicine, Cardamone said. "These machines could operate in solution, in vivo. There already are clinical trials of nanoparticles to deliver medicinal drugs. Imagine how much more powerful those little nanoparticles or nanorobots would be if they could count, or do simple computation. With our transistors packed at maximum density, you could put a microprocessor as powerful as the top-of-the-line workstation on the back of an E. coli."
"Have you seen the movie, Fantastic Voyage?" Stafford asked. A nano-sized surgical team journeyed through a human body in the 1966 sci-fi flick. That's a different story, but with a similar theme.

"We're not futurists at all and can't predict it, but imagine that you could make an artificial intelligence, that you could have this little submarine that goes inside somebody's arteries and capillaries to repair them," Stafford said.