https://www.sciencedaily.com/news/plants_animals/bird_flu/ Bird Flu news. Read current news and research on risks of a bird flu pandemic, responses, medication and vaccines. Everything on H5N1, the avian flu virus. en-us Sat, 18 Apr 2026 12:00:43 EDT Sat, 18 Apr 2026 12:00:43 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/plants_animals/bird_flu/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/02/260211073029.htm For the first time, deadly H5N1 bird flu has been confirmed as the cause of a wildlife die-off in Antarctica, killing more than 50 skuas during the 2023–2024 summers. Researchers on an Antarctic expedition found the virus ravaging these powerful seabirds, with some suffering severe neurological symptoms—twisted necks, circling behavior, and even falling from the sky. While penguins and fur seals were examined, skuas emerged as the primary victims, especially on Beak Island, where a mass die-off occurred. Thu, 12 Feb 2026 01:31:45 EST https://www.sciencedaily.com/releases/2026/02/260211073029.htm https://www.sciencedaily.com/releases/2025/11/251128050503.htm Researchers discovered why bird flu can survive temperatures that stop human flu in its tracks. A key gene, PB1, gives avian viruses the ability to replicate even at fever-level heat. Mice experiments confirmed that fever cripples human-origin flu but not avian strains, especially those with avian-like PB1. These findings highlight how gene swapping could fuel future pandemics. Fri, 28 Nov 2025 07:37:38 EST https://www.sciencedaily.com/releases/2025/11/251128050503.htm https://www.sciencedaily.com/releases/2025/05/250515145628.htm A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven't worked -- largely because HIV mutates rapidly and hides key parts of itself from the immune system. Now, a new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them -- a key step toward a long-sought goal in vaccine development. Thu, 15 May 2025 14:56:28 EDT https://www.sciencedaily.com/releases/2025/05/250515145628.htm https://www.sciencedaily.com/releases/2025/05/250509122258.htm A research team has achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV). These innovative LAIV platforms offer potential to develop universal influenza vaccines that induce a more robust immune response against various virus subtypes, including both human and avian strains. Fri, 09 May 2025 12:22:58 EDT https://www.sciencedaily.com/releases/2025/05/250509122258.htm https://www.sciencedaily.com/releases/2025/05/250508112443.htm The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally developed for smallpox, is a promising option for countering the mpox virus. Exploring this potential further, researchers employed a cross-species immunological analysis to provide new insights into LC16m8's immunogenicity and safety against mpox. The recent global monkeypox (mpox) outbreak, with a new and aggressive variant, has underscored the dire need for safe, broadly effective, and accessible vaccines. The LC16m8 vaccine, an attenuated vaccinia virus strain originally developed for smallpox, is a promising option for countering the mpox virus. Exploring this potential further, researchers employed a cross-species immunological analysis to provide new insights into LC16m8's immunogenicity and safety against mpox. Thu, 08 May 2025 11:24:43 EDT https://www.sciencedaily.com/releases/2025/05/250508112443.htm https://www.sciencedaily.com/releases/2025/05/250508112429.htm Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Thu, 08 May 2025 11:24:29 EDT https://www.sciencedaily.com/releases/2025/05/250508112429.htm https://www.sciencedaily.com/releases/2025/04/250417145009.htm A vaccine under development has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu. The work focuses on the H5N1 variant known as 2.3.4.4b, which has caused widespread outbreaks in wild birds and poultry and other mammals. The vaccine is step toward more potent, versatile and easy-to-produce vaccines that public health officials believe will be needed to counteract evolving bird flu strains that grow resistant to existing vaccines. Thu, 17 Apr 2025 14:50:09 EDT https://www.sciencedaily.com/releases/2025/04/250417145009.htm https://www.sciencedaily.com/releases/2025/04/250408122112.htm Scientists have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine. During the early COVID-19 pandemic, this platform enabled the rapid development of a nasal spray vaccine in collaboration with mainland China's Wantai BioPharm. After completing Phase 1-3 clinical trials, it was approved in 2022 as the world's first nasal spray COVID-19 vaccine. Tue, 08 Apr 2025 12:21:12 EDT https://www.sciencedaily.com/releases/2025/04/250408122112.htm https://www.sciencedaily.com/releases/2025/04/250408121657.htm Researchers have shown that differences in the entire rotavirus genome -- not just its two surface proteins -- affect how well vaccines work, helping to explain why some strains are more likely to infect vaccinated individuals. Tue, 08 Apr 2025 12:16:57 EDT https://www.sciencedaily.com/releases/2025/04/250408121657.htm https://www.sciencedaily.com/releases/2025/04/250404201407.htm Low vaccination rates for influenza viruses and the lack of an HSV vaccine underscore the need for a new approach to reduce viral transmission. Researchers have now used a clinical-grade antiviral chewing gum to substantially reduce viral loads of two herpes simplex viruses and two influenza A strains in experimental models. Fri, 04 Apr 2025 20:14:07 EDT https://www.sciencedaily.com/releases/2025/04/250404201407.htm https://www.sciencedaily.com/releases/2025/04/250402122149.htm A unique vaccination rollout in Wales offered researchers a natural experiment: some older adults qualified for the shingles vaccine, while others just missed the cutoff. The results were striking — those who got the shot had a 20% lower risk of developing dementia within seven years. This breakthrough hints that viruses lurking in the nervous system may contribute to dementia and that prevention could be simpler than anyone imagined. Wed, 02 Apr 2025 12:21:49 EDT https://www.sciencedaily.com/releases/2025/04/250402122149.htm https://www.sciencedaily.com/releases/2025/03/250317184329.htm Existing antivirals may be less effective against this H5N1 bird flu strain, and prevention measures, such as avoiding raw milk consumption and reducing exposure in dairy workers, may be the most effective way to protect against the virus. Mon, 17 Mar 2025 18:43:29 EDT https://www.sciencedaily.com/releases/2025/03/250317184329.htm https://www.sciencedaily.com/releases/2025/03/250313180452.htm Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection against H5N1, and children would benefit more from H5N1 vaccines. Thu, 13 Mar 2025 18:04:52 EDT https://www.sciencedaily.com/releases/2025/03/250313180452.htm https://www.sciencedaily.com/releases/2025/03/250305135134.htm A live-attenuated tuberculosis (TB) vaccine candidate in development elicits a much more balanced and effective immune response compared to the existing vaccine used across much of the world, according to preclinical research. Wed, 05 Mar 2025 13:51:34 EST https://www.sciencedaily.com/releases/2025/03/250305135134.htm https://www.sciencedaily.com/releases/2025/02/250226175926.htm Pre-existing immunity against seasonal H1N1 flu might help explain why most reported human cases of H5N1 bird flu in the U.S. have not resulted in lethal outcomes. Wed, 26 Feb 2025 17:59:26 EST https://www.sciencedaily.com/releases/2025/02/250226175926.htm https://www.sciencedaily.com/releases/2025/02/250219110112.htm New research has yielded promising results in the fight against campylobacter in free-range chicken flocks. Trials demonstrate that adding biochar to chicken feed can reduce campylobacter in chickens by up to 80%. This could potentially lead to fewer foodborne illnesses among humans. Wed, 19 Feb 2025 11:01:12 EST https://www.sciencedaily.com/releases/2025/02/250219110112.htm https://www.sciencedaily.com/releases/2025/01/250130161626.htm The antibody targets a stable part of the bird flu virus, ensuring that the immune protection can resist new variants and offer long-term protection against the globally spreading airborne infection. Thu, 30 Jan 2025 16:16:26 EST https://www.sciencedaily.com/releases/2025/01/250130161626.htm https://www.sciencedaily.com/releases/2025/01/250115125058.htm Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective. Wed, 15 Jan 2025 12:50:58 EST https://www.sciencedaily.com/releases/2025/01/250115125058.htm https://www.sciencedaily.com/releases/2025/01/250102162519.htm Highly pathogenic H5N1 avian influenza A virus (HPAI H5N1) remains a low risk to the general public, and public health experts in the United States believe that available treatments and vaccines, as well as those in development, are sufficient to prevent severe disease. Thu, 02 Jan 2025 16:25:19 EST https://www.sciencedaily.com/releases/2025/01/250102162519.htm https://www.sciencedaily.com/releases/2024/12/241219151655.htm Stitching together four molecules found in the standard flu vaccine ensures an immune response to all of them, scientists have shown. Thu, 19 Dec 2024 15:16:55 EST https://www.sciencedaily.com/releases/2024/12/241219151655.htm https://www.sciencedaily.com/releases/2024/12/241206162110.htm A single modification in the protein found on the surface of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus currently circulating in U.S. dairy cows could allow for easier transmission among humans, according to new research. The study results reinforce the need for continued, vigilant surveillance and monitoring of HPAI H5N1 for potential genetic changes that could make the virus more transmissible in humans. Fri, 06 Dec 2024 16:21:10 EST https://www.sciencedaily.com/releases/2024/12/241206162110.htm https://www.sciencedaily.com/releases/2024/12/241205142418.htm Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus? A recent study reveals that a single mutation in the H5N1 'bird flu' virus that has recently infected dairy cows in the U.S. could enhance the virus' ability to attach to human cells, potentially increasing the risk of passing from person to person. The findings highlight the need to monitor H5N1's evolution. Thu, 05 Dec 2024 14:24:18 EST https://www.sciencedaily.com/releases/2024/12/241205142418.htm https://www.sciencedaily.com/releases/2024/12/241204183117.htm By comparing cancer incidence rates with genomic surveillance data, researchers suggest that higher rates of certain cancers in the UK and other countries may be linked to two bacterial strains. These strains are also among the most frequent causes of urinary tract infections. Wed, 04 Dec 2024 18:31:17 EST https://www.sciencedaily.com/releases/2024/12/241204183117.htm https://www.sciencedaily.com/releases/2024/11/241119132323.htm A research article shows that Eradivir's patent-pending antiviral therapeutic called EV25 reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively than currently available therapies. Tue, 19 Nov 2024 13:23:23 EST https://www.sciencedaily.com/releases/2024/11/241119132323.htm https://www.sciencedaily.com/releases/2024/11/241113123430.htm An FDA-approved vaccine for smallpox and mpox is effective but causes side effects. The other requires multiple doses. An experimental single-dose vaccine uses the horsepox virus to harness the benefits of both strategies. Wed, 13 Nov 2024 12:34:30 EST https://www.sciencedaily.com/releases/2024/11/241113123430.htm https://www.sciencedaily.com/releases/2024/11/241113123311.htm Why do some people develop severe flu symptoms? A study points the finger at an unsung portion of the antibodies our immune systems generate to fend off invading pathogens. Wed, 13 Nov 2024 12:33:11 EST https://www.sciencedaily.com/releases/2024/11/241113123311.htm https://www.sciencedaily.com/releases/2024/11/241111123200.htm A year after an outbreak of H5N1 killed thousands of elephant seals in Argentina, only about a third of the seals normally expected here returned, scientists estimate. Mon, 11 Nov 2024 12:32:00 EST https://www.sciencedaily.com/releases/2024/11/241111123200.htm https://www.sciencedaily.com/releases/2024/11/241106132501.htm An epidemiological study found that 56 percent of a large breeding colony of Caspian terns died from a 2023 outbreak of highly pathogenic avian influenza at Rat Island in Washington state. Researchers also documented that the avian flu virus H5N1 was transmitted to harbor seals for the first time in the northeastern Pacific. Wed, 06 Nov 2024 13:25:01 EST https://www.sciencedaily.com/releases/2024/11/241106132501.htm https://www.sciencedaily.com/releases/2024/10/241028131451.htm A strain of H5N1 avian influenza virus found in a Texas dairy worker who was infected this spring was able to spread among ferrets through the air, although inefficiently, and killed 100% of infected animals in studies researchers performed with the strain earlier this year. Mon, 28 Oct 2024 13:14:51 EDT https://www.sciencedaily.com/releases/2024/10/241028131451.htm https://www.sciencedaily.com/releases/2024/09/240916115428.htm If seabirds can catch avian flu by stealing food from infectious birds, it gives scientists a clue where to monitor for outbreaks among these vulnerable birds. Mon, 16 Sep 2024 11:54:28 EDT https://www.sciencedaily.com/releases/2024/09/240916115428.htm https://www.sciencedaily.com/releases/2024/09/240912135656.htm A promising Lassa fever vaccine shows potential to prevent severe disease and death in animals. Thu, 12 Sep 2024 13:56:56 EDT https://www.sciencedaily.com/releases/2024/09/240912135656.htm https://www.sciencedaily.com/releases/2024/09/240911180009.htm Avian influenza A(H5N1) virus, which spread to cattle and infected 14 people this year, was detected using virome sequencing in the wastewater of 10 Texas cities. Wed, 11 Sep 2024 18:00:09 EDT https://www.sciencedaily.com/releases/2024/09/240911180009.htm https://www.sciencedaily.com/releases/2024/09/240904130825.htm The most frequently used mpox vaccine provides partial immunity to the disease but isn't always able to prevent severe symptoms or disease transmission. A new vaccine candidate from Moderna, mRNA-1769, more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a currently licensed modified vaccinia Ankara (MVA) vaccine. Wed, 04 Sep 2024 13:08:25 EDT https://www.sciencedaily.com/releases/2024/09/240904130825.htm https://www.sciencedaily.com/releases/2024/09/240904130810.htm As the global threat of H5N1 influenza looms with outbreaks across species and continents including the U.S., three international vaccine and public health experts say it is time to fully resource and support a robust strategy to address this and future potential pandemic influenza threats, including to consider voluntary vaccination for those now at exposure risk. Wed, 04 Sep 2024 13:08:10 EDT https://www.sciencedaily.com/releases/2024/09/240904130810.htm https://www.sciencedaily.com/releases/2024/08/240822125918.htm A new flu vaccine candidate incorporates proteins from 8 strains of influenza. Thu, 22 Aug 2024 12:59:18 EDT https://www.sciencedaily.com/releases/2024/08/240822125918.htm https://www.sciencedaily.com/releases/2024/08/240819130740.htm The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species. Mon, 19 Aug 2024 13:07:40 EDT https://www.sciencedaily.com/releases/2024/08/240819130740.htm https://www.sciencedaily.com/releases/2024/08/240814185758.htm Recent trials of an experimental malaria vaccine in healthy Malian adults found that all three tested regimens were safe. One of the trials enrolled 300 healthy women ages 18 to 38 years who anticipated becoming pregnant soon after immunization. That trial began with drug treatment to remove malaria parasites, followed by three injections spaced over a month of either saline placebo or the investigational vaccine at one of two dosages. Wed, 14 Aug 2024 18:57:58 EDT https://www.sciencedaily.com/releases/2024/08/240814185758.htm https://www.sciencedaily.com/releases/2024/08/240812160250.htm Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes. Mon, 12 Aug 2024 16:02:50 EDT https://www.sciencedaily.com/releases/2024/08/240812160250.htm https://www.sciencedaily.com/releases/2024/08/240809135948.htm A new, two-step flu vaccination strategy that pairs intramuscular injection of a viral vectored flu vaccine with nasal spray administration of a novel attenuated live flu virus appears to be safe and effective in pigs, researchers report. Fri, 09 Aug 2024 13:59:48 EDT https://www.sciencedaily.com/releases/2024/08/240809135948.htm https://www.sciencedaily.com/releases/2024/07/240731170756.htm A nasal COVID-19 vaccine blocks transmission of the virus, according to an animal study. The findings suggest that vaccines delivered directly to the nose or mouth could play a critical role in containing the spread of respiratory infections. Wed, 31 Jul 2024 17:07:56 EDT https://www.sciencedaily.com/releases/2024/07/240731170756.htm https://www.sciencedaily.com/releases/2024/07/240725154643.htm Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death. The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other viral diseases. Thu, 25 Jul 2024 15:46:43 EDT https://www.sciencedaily.com/releases/2024/07/240725154643.htm https://www.sciencedaily.com/releases/2024/07/240724122226.htm A new study provides evidence that a spillover of avian influenza from birds to dairy cattle across several U.S. states has now led to mammal-to-mammal transmission -- between cows and from cows to cats and a raccoon. Wed, 24 Jul 2024 12:22:26 EDT https://www.sciencedaily.com/releases/2024/07/240724122226.htm https://www.sciencedaily.com/releases/2024/07/240708222405.htm While H5N1 avian influenza virus taken from infected cow's milk makes mice and ferrets sick when dripped into their noses, airborne transmission of the virus between ferrets -- a common model for human transmission -- appears to be limited. These and other new findings about the strain of H5N1 circulating among North American dairy cattle this year come from a set of laboratory experiments. Together, they suggest that exposure to raw milk infected with the currently circulating virus poses a real risk of infecting humans, but that the virus may not spread very far or quickly to others. Mon, 08 Jul 2024 22:24:05 EDT https://www.sciencedaily.com/releases/2024/07/240708222405.htm https://www.sciencedaily.com/releases/2024/07/240703131735.htm Researchers found no infectious virus in the sampled pasteurized milk products tested for H5N1. Wed, 03 Jul 2024 13:17:35 EDT https://www.sciencedaily.com/releases/2024/07/240703131735.htm https://www.sciencedaily.com/releases/2024/06/240627172039.htm H5N1 virus in unpasteurized milk is stable on metal and rubber components of commercial milking equipment for at least one hour, increasing its potential to infect people and other animals. Thu, 27 Jun 2024 17:20:39 EDT https://www.sciencedaily.com/releases/2024/06/240627172039.htm https://www.sciencedaily.com/releases/2024/06/240621172402.htm Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment. Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. The test uses CRISPR to distinguish between the two main types of seasonal flu, influenza A and B, as well as seasonal flu subtypes H1N1 and H3N2. It can also identify strains that resist antiviral treatment, and with further work, could potentially detect swine and avian flu strains, including H5N1, which is currently infecting cattle. Fri, 21 Jun 2024 17:24:02 EDT https://www.sciencedaily.com/releases/2024/06/240621172402.htm https://www.sciencedaily.com/releases/2024/06/240614141822.htm The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research. However, small, detectable amounts of infectious virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius (161.6 degrees Fahrenheit) for 15 seconds -- one of the standard pasteurization methods used by the dairy industry. The authors of the study stress, however, that their findings reflect experimental conditions in a laboratory setting and are not identical to large-scale industrial pasteurization processes for raw milk. Fri, 14 Jun 2024 14:18:22 EDT https://www.sciencedaily.com/releases/2024/06/240614141822.htm https://www.sciencedaily.com/releases/2024/05/240529031235.htm Review of research to-date suggests vaccination remains the most effective strategy for avian influenza prevention and control in humans, despite varying vaccine efficacy across strains. Wed, 29 May 2024 03:12:35 EDT https://www.sciencedaily.com/releases/2024/05/240529031235.htm https://www.sciencedaily.com/releases/2024/05/240524171418.htm Researchers discovered that people who experienced symptomatic breakthrough infections develop T cells that are better at recognizing and targeting SARS-CoV-2, including the Omicron and Delta variants. The researchers describe this increased protection as an 'immunity wall.' Fri, 24 May 2024 17:14:18 EDT https://www.sciencedaily.com/releases/2024/05/240524171418.htm https://www.sciencedaily.com/releases/2024/05/240524121634.htm Mice administered raw milk samples from dairy cows infected with H5N1 influenza experienced high virus levels in their respiratory organs and lower virus levels in other vital organs, according to new findings. The results suggest that consumption of raw milk by animals poses a risk for H5N1 infection and raises questions about its potential risk in humans. Fri, 24 May 2024 12:16:34 EDT https://www.sciencedaily.com/releases/2024/05/240524121634.htm https://www.sciencedaily.com/releases/2024/05/240521132302.htm Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection. Tue, 21 May 2024 13:23:02 EDT https://www.sciencedaily.com/releases/2024/05/240521132302.htm https://www.sciencedaily.com/releases/2024/05/240515164238.htm Highly pathogenic H5N1 avian influenza was detected in dairy cattle for the first time in the United States in March, with nine states reporting outbreaks by May. While the method of transmission among cattle is currently unknown, new research demonstrates that a related strain of H5N1, subtype clade 2.3.4.4b, which caused an outbreak in farmed mink in 2022, transmitted through the air to a limited number of ferrets. This is the first time that a member of the group of H5N1 clade 2.3.4.4b viruses has been shown to exhibit this ability. According to the researchers, the findings suggest these viruses are evolving to infect mammals and with potentially increased risk to humans. Wed, 15 May 2024 16:42:38 EDT https://www.sciencedaily.com/releases/2024/05/240515164238.htm https://www.sciencedaily.com/releases/2024/05/240515122731.htm A small number of New York City wild birds carry highly pathogenic H5N1 avian influenza, according to a recent study. Wed, 15 May 2024 12:27:31 EDT https://www.sciencedaily.com/releases/2024/05/240515122731.htm https://www.sciencedaily.com/releases/2024/05/240506131603.htm Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks -- including ones we don't even know about. Mon, 06 May 2024 13:16:03 EDT https://www.sciencedaily.com/releases/2024/05/240506131603.htm https://www.sciencedaily.com/releases/2024/03/240301134742.htm Researchers have identified antibodies targeting a hard-to-spot region of the influenza virus, shedding light on the relatively unexplored 'dark side' of the neuraminidase (NA) protein head. The antibodies target a region of the NA protein that is common among many influenza viruses, including H3N2 subtype viruses, and could be a new target for countermeasures. Fri, 01 Mar 2024 13:47:42 EST https://www.sciencedaily.com/releases/2024/03/240301134742.htm https://www.sciencedaily.com/releases/2024/02/240228115447.htm Avian influenza virus H5N1 has adapted to spread between birds and marine mammals, finds a new study. Wed, 28 Feb 2024 11:54:47 EST https://www.sciencedaily.com/releases/2024/02/240228115447.htm https://www.sciencedaily.com/releases/2024/02/240220144618.htm Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy. Tue, 20 Feb 2024 14:46:18 EST https://www.sciencedaily.com/releases/2024/02/240220144618.htm https://www.sciencedaily.com/releases/2024/02/240213130423.htm Researchers have shed new light on how viral evolution, population immunity, and the co-circulation of other flu viruses shape seasonal flu epidemics. Tue, 13 Feb 2024 13:04:23 EST https://www.sciencedaily.com/releases/2024/02/240213130423.htm https://www.sciencedaily.com/releases/2024/02/240206144907.htm Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a new study. Tue, 06 Feb 2024 14:49:07 EST https://www.sciencedaily.com/releases/2024/02/240206144907.htm https://www.sciencedaily.com/releases/2024/01/240130133628.htm Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2. Tue, 30 Jan 2024 13:36:28 EST https://www.sciencedaily.com/releases/2024/01/240130133628.htm