https://www.sciencedaily.com/news/health_medicine/hypertension/ Hypertension. Read about the latest medical research on reducing high blood pressure, treatment options for hypertension and more. en-us Wed, 11 Mar 2026 06:27:59 EDT Wed, 11 Mar 2026 06:27:59 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/hypertension/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/03/260302030648.htm Researchers are developing a two-part therapy for type 1 diabetes: lab-made insulin-producing cells paired with custom-engineered immune cells that protect them. The goal is to stop the immune system from destroying transplanted cells — without using immunosuppressive drugs. Backed by $1 million in funding, the team hopes to create a ready-to-use treatment that could work even for people who have had diabetes for years. The approach could transform how the disease is treated. Mon, 02 Mar 2026 11:49:16 EST https://www.sciencedaily.com/releases/2026/03/260302030648.htm https://www.sciencedaily.com/releases/2026/02/260227061818.htm Heart disease is on track to tighten its grip on American women. New projections from the American Heart Association warn that over the next 25 years, cardiovascular disease will rise sharply, driven largely by a surge in high blood pressure, diabetes, and obesity. By 2050, nearly 60% of women in the U.S. could have high blood pressure, and close to one in three women ages 22 to 44 may already be living with some form of heart disease. Fri, 27 Feb 2026 06:18:18 EST https://www.sciencedaily.com/releases/2026/02/260227061818.htm https://www.sciencedaily.com/releases/2026/02/260212234212.htm A low-fat vegan diet—without cutting calories or carbs—may help people with type 1 diabetes significantly reduce how much insulin they need, and how much they spend on it. In a new analysis published in BMC Nutrition, participants following the plant-based plan lowered their daily insulin use by 28%, while those on a portion-controlled diet saw no meaningful change. Fri, 13 Feb 2026 02:30:08 EST https://www.sciencedaily.com/releases/2026/02/260212234212.htm https://www.sciencedaily.com/releases/2026/02/260211073033.htm Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity. But while the results are impressive, researchers caution that most trials were funded by drugmakers, long term safety data are still limited, and side effects such as nausea are common. Wed, 11 Feb 2026 10:01:13 EST https://www.sciencedaily.com/releases/2026/02/260211073033.htm https://www.sciencedaily.com/releases/2026/01/260131082433.htm Lowering salt in everyday foods could quietly save lives. Researchers found that modest sodium reductions in bread, packaged foods, and takeout meals could significantly reduce heart disease and stroke rates in France and the U.K. The key advantage is that people would not need to alter their eating habits at all. Small changes to the food supply could deliver large, long-term health benefits. Sat, 31 Jan 2026 09:27:42 EST https://www.sciencedaily.com/releases/2026/01/260131082433.htm https://www.sciencedaily.com/releases/2026/01/260129080443.htm Collagen pills sound like a shortcut to younger skin, but solid evidence doesn’t back them up. Higher-quality studies show little benefit, and your body doesn’t absorb collagen in the way ads suggest. Some supplements may even pose safety concerns and lack proper testing. Experts recommend focusing on proven habits like sunscreen, retinoids, and a nutrient-rich diet instead. Thu, 29 Jan 2026 23:30:21 EST https://www.sciencedaily.com/releases/2026/01/260129080443.htm https://www.sciencedaily.com/releases/2025/12/251213032615.htm Researchers used a deep learning AI model to uncover the first imaging-based biomarker of chronic stress by measuring adrenal gland volume on routine CT scans. This new metric, the Adrenal Volume Index, correlates strongly with cortisol levels, allostatic load, perceived stress, and even long-term cardiovascular outcomes, including heart failure risk. Sun, 14 Dec 2025 09:27:30 EST https://www.sciencedaily.com/releases/2025/12/251213032615.htm https://www.sciencedaily.com/releases/2025/11/251118220041.htm Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments that keep the benefits of weight loss while reducing unwanted side effects. Tue, 18 Nov 2025 22:48:02 EST https://www.sciencedaily.com/releases/2025/11/251118220041.htm https://www.sciencedaily.com/releases/2025/11/251116105627.htm GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress the need for independent studies before these treatments can be fully embraced worldwide. Sun, 16 Nov 2025 22:39:45 EST https://www.sciencedaily.com/releases/2025/11/251116105627.htm https://www.sciencedaily.com/releases/2025/10/251022023118.htm A wireless eye implant developed at Stanford Medicine has restored reading ability to people with advanced macular degeneration. The PRIMA chip works with smart glasses to replace lost photoreceptors using infrared light. Most trial participants regained functional vision, reading books and recognizing signs. Researchers are now developing higher-resolution versions that could eventually provide near-normal sight. Wed, 22 Oct 2025 10:26:46 EDT https://www.sciencedaily.com/releases/2025/10/251022023118.htm https://www.sciencedaily.com/releases/2025/10/251008030947.htm A new pill called baxdrostat may offer hope for people whose blood pressure stays high even after taking standard medications. In a recent study, the drug lowered blood pressure and also seemed to protect the kidneys by reducing signs of damage. Doctors say this could help millions of people with chronic kidney disease, a condition that often makes blood pressure harder to control. Wed, 08 Oct 2025 23:01:32 EDT https://www.sciencedaily.com/releases/2025/10/251008030947.htm https://www.sciencedaily.com/releases/2025/09/250920214455.htm Duke University scientists have discovered that pancreatic alpha cells, long believed to only produce glucagon, actually generate powerful amounts of GLP-1 — the same hormone mimicked by popular diabetes drugs like semaglutide (Ozempic and Wegovy). Even more surprisingly, when glucagon production is blocked, alpha cells “switch gears” and boost GLP-1 output, enhancing insulin release and blood sugar control. Sun, 21 Sep 2025 08:45:57 EDT https://www.sciencedaily.com/releases/2025/09/250920214455.htm https://www.sciencedaily.com/releases/2025/09/250907172611.htm Children with higher blood pressure as young as age 7 face a sharply increased risk of dying from cardiovascular disease by their mid-50s, according to a massive decades-long study. Researchers found that even moderately elevated readings, not just full hypertension, raised the danger, with risks climbing as much as 40–50%. Sun, 07 Sep 2025 18:51:58 EDT https://www.sciencedaily.com/releases/2025/09/250907172611.htm https://www.sciencedaily.com/releases/2025/08/250831010541.htm A breakthrough pill, baxdrostat, has shown remarkable success in lowering dangerously high blood pressure in patients resistant to standard treatments. In a large international trial, it cut systolic pressure by nearly 10 mmHg, enough to significantly reduce risks of heart attack, stroke, and kidney disease. The drug works by blocking excess aldosterone, a hormone that drives uncontrolled hypertension. Sun, 31 Aug 2025 11:24:23 EDT https://www.sciencedaily.com/releases/2025/08/250831010541.htm https://www.sciencedaily.com/releases/2025/08/250831010539.htm Beta blockers, used for decades after heart attacks, provide no benefit for patients with preserved heart function, according to the REBOOT trial. The massive study also found women faced higher risks when taking the drug. Experts say the results will change heart treatment guidelines worldwide. Sun, 31 Aug 2025 11:03:07 EDT https://www.sciencedaily.com/releases/2025/08/250831010539.htm https://www.sciencedaily.com/releases/2025/07/250705084253.htm Scientists have pioneered a new way to monitor sodium levels in the blood—without drawing a single drop. By combining terahertz radiation and optoacoustic detection, they created a non-invasive system that tracks sodium in real time, even through skin. The approach bypasses traditional barriers like water interference and opens up potential for fast, safe diagnostics in humans. Sun, 06 Jul 2025 04:16:03 EDT https://www.sciencedaily.com/releases/2025/07/250705084253.htm https://www.sciencedaily.com/releases/2025/05/250528132235.htm An analysis of data from a national health survey conducted before the pandemic found that pizza, soup and chicken are some of the main sources of sodium (salt) intake for people in all racial and ethnic groups. The study also showed clear differences among adults based on race and ethnicity. Wed, 28 May 2025 13:22:35 EDT https://www.sciencedaily.com/releases/2025/05/250528132235.htm https://www.sciencedaily.com/releases/2025/05/250523120353.htm Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Fri, 23 May 2025 12:03:53 EDT https://www.sciencedaily.com/releases/2025/05/250523120353.htm https://www.sciencedaily.com/releases/2025/05/250521124809.htm A new risk calculator accurately identified participants who had calcium buildup in their heart arteries and those who had a higher future heart attack risk, in an analysis of about 7,000 adults in New York City referred for heart disease screening. Wed, 21 May 2025 12:48:09 EDT https://www.sciencedaily.com/releases/2025/05/250521124809.htm https://www.sciencedaily.com/releases/2025/05/250520122031.htm Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted. Tue, 20 May 2025 12:20:31 EDT https://www.sciencedaily.com/releases/2025/05/250520122031.htm https://www.sciencedaily.com/releases/2025/05/250512165549.htm Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost estrogen-related receptors could be a powerful way to restore energy supplies in people with metabolic disorders, such as muscular dystrophy. Mon, 12 May 2025 16:55:49 EDT https://www.sciencedaily.com/releases/2025/05/250512165549.htm https://www.sciencedaily.com/releases/2025/04/250430141618.htm Researchers have identified biomarkers for tinnitus severity in subtle facial movements and pupil dilation that can be captured on video recordings. Until now, there has been no objective way to measure tinnitus severity and clinicians rely on patient survey questionnaires. The researchers plan to use these biomarkers to develop and test new therapies that can reduce or eliminate the phantom sounds (i.e. ringing in the ears) caused by tinnitus. Wed, 30 Apr 2025 14:16:18 EDT https://www.sciencedaily.com/releases/2025/04/250430141618.htm https://www.sciencedaily.com/releases/2025/04/250409154607.htm Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, Cilengitide, was found to reduce kidney scarring and slow disease progression in preclinical models, suggesting a possible precision medicine approach for high-risk patients. The team now seeks to develop a blood test to measure type 5 collagen levels, which could help identify patients at greater risk for kidney failure and guide targeted treatment strategies. Wed, 09 Apr 2025 15:46:07 EDT https://www.sciencedaily.com/releases/2025/04/250409154607.htm https://www.sciencedaily.com/releases/2025/04/250408121806.htm Calcium transport into and out of mitochondria -- the powerhouses of cells -- is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, cells rely on a protein known as the mitochondrial sodium-calcium exchanger, or NCLX. Now, in new research, scientists have discovered a novel regulator of NCLX activity, a protein called TMEM65, which helps move calcium out of mitochondria, protecting against harmful calcium overload. Tue, 08 Apr 2025 12:18:06 EDT https://www.sciencedaily.com/releases/2025/04/250408121806.htm https://www.sciencedaily.com/releases/2025/04/250408121706.htm Research shows that the biological parents' genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Tue, 08 Apr 2025 12:17:06 EDT https://www.sciencedaily.com/releases/2025/04/250408121706.htm https://www.sciencedaily.com/releases/2025/03/250326221519.htm People who have early signs of heart problems may also have changes in brain health that can be early signs of dementia, such as loss of brain volume, according to a meta-analysis. The meta-analysis does not prove that early heart problems cause loss of brain cells; it only shows an association. Wed, 26 Mar 2025 22:15:19 EDT https://www.sciencedaily.com/releases/2025/03/250326221519.htm https://www.sciencedaily.com/releases/2025/03/250320145457.htm Mammograms, with the help of artificial intelligence (AI) models, may reveal much more than cancer, according to a new study. The findings highlight how these important cancer screening tools can also be used to assess the amount of calcium buildup in the arteries within breast tissue -- an indicator of cardiovascular health. Thu, 20 Mar 2025 14:54:57 EDT https://www.sciencedaily.com/releases/2025/03/250320145457.htm https://www.sciencedaily.com/releases/2025/03/250312124325.htm Challenging the long-standing belief that fibroblasts produce skin collagen, researchers have investigated collagen formation in the 'glass-skinned' amphibian axolotl and other vertebrates. They discovered that keratinocytes, the surface cells of the skin, are responsible for producing collagen, which is then transferred deeper to form the dermis. Later, fibroblasts migrate into this collagen layer, modifying and reinforcing its structure. Wed, 12 Mar 2025 12:43:25 EDT https://www.sciencedaily.com/releases/2025/03/250312124325.htm https://www.sciencedaily.com/releases/2025/03/250306122911.htm Certain glycans -- sugar-like compounds with carbohydrate chains -- containing galactose, may exhibit potential prebiotic properties that support human health. Identifying enzymes capable of breaking down these glycans is essential for unlocking their full potential. In a new study, researchers discovered a novel enzyme in the human gut that specifically targets a previously unexplored glycan called -1,2-galactooligosaccharide, known for their prebiotic benefits. This discovery can open new avenues in prebiotic research, potentially enhancing human health. Thu, 06 Mar 2025 12:29:11 EST https://www.sciencedaily.com/releases/2025/03/250306122911.htm https://www.sciencedaily.com/releases/2025/03/250304113808.htm Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 diabetes (T2D). These findings could lead to promising treatments targeting beta cell dysfunction. Tue, 04 Mar 2025 11:38:08 EST https://www.sciencedaily.com/releases/2025/03/250304113808.htm https://www.sciencedaily.com/releases/2025/02/250224155104.htm Researchers have uncovered a surprising layer of complexity in aldosterone-producing adenomas -- adrenal gland tumors that drive high blood pressure. Using cutting-edge analysis techniques, they discovered that these tumors harbor at least four distinct cell types, including ones that produce cortisol, the body's main stress hormone. Their findings not only explain why some patients with these tumors develop unexpected health issues, like weakened bones, but also pave the way toward new treatment strategies. Mon, 24 Feb 2025 15:51:04 EST https://www.sciencedaily.com/releases/2025/02/250224155104.htm https://www.sciencedaily.com/releases/2025/02/250224111937.htm Diabetes and obesity have become pressing health issues worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications widely used in the treatment of type 2 diabetes (T2D), have shown significant effectiveness in both lowering blood sugar levels and aiding weight loss due to their unique pharmacological mechanisms. A research team assessed the impact of GLP-1 receptor agonist in weight loss through genetic studies, aiming to understand whether the use of these medications reduces weight due to muscle or fat mass loss. This genetic study revealed that GLP-1 receptor agonists reduce weight by reducing more fat mass than muscle mass. Mon, 24 Feb 2025 11:19:37 EST https://www.sciencedaily.com/releases/2025/02/250224111937.htm https://www.sciencedaily.com/releases/2025/02/250219105949.htm Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to facilitate the uptake of glucose through tissues and organs, leading to an increase in blood glucose (chronic hyperglycaemia). Since skeletal muscle is the tissue that uses the most glucose in response to insulin action, it is the most affected tissue by insulin resistance. Wed, 19 Feb 2025 10:59:49 EST https://www.sciencedaily.com/releases/2025/02/250219105949.htm https://www.sciencedaily.com/releases/2025/02/250212140910.htm South Asian adults in the United Kingdom may face high blood pressure-related heart risks earlier in life, while East Asian adults see risks rise in later years, according to a new study. Wed, 12 Feb 2025 14:09:10 EST https://www.sciencedaily.com/releases/2025/02/250212140910.htm https://www.sciencedaily.com/releases/2025/02/250210132401.htm A revolutionary new treatment called Targeted Thermal Therapy (Tripel T) offers a safer, faster alternative to surgery for patients with high blood pressure caused by Primary Aldosteronism, a hormonal disorder. Mon, 10 Feb 2025 13:24:01 EST https://www.sciencedaily.com/releases/2025/02/250210132401.htm https://www.sciencedaily.com/releases/2025/02/250207122444.htm Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues. However, a new study challenges that notion, revealing an unexpected confirmation in collagen structure that could reshape biomedical research. Fri, 07 Feb 2025 12:24:44 EST https://www.sciencedaily.com/releases/2025/02/250207122444.htm https://www.sciencedaily.com/releases/2025/02/250205131253.htm Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists may alleviate IBS symptoms by acting directly on the central nervous system. Using a novel stress-induced mouse model, they found these drugs reduce abdominal pain and regulate bowel movements. This research suggests a promising approach to treating IBS by targeting stress as a contributing factor. Wed, 05 Feb 2025 13:12:53 EST https://www.sciencedaily.com/releases/2025/02/250205131253.htm https://www.sciencedaily.com/releases/2025/01/250123224039.htm Scientists have shown that specialized cells involved in how the body responds to insulin are activated in the brain after exercise, suggesting that physical activity may directly improve brain function. Thu, 23 Jan 2025 22:40:39 EST https://www.sciencedaily.com/releases/2025/01/250123224039.htm https://www.sciencedaily.com/releases/2025/01/250117161113.htm Researchers have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick. The study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells. These disruptions in calcium signaling affect rotavirus disease severity, providing new insights into how NSP4's function influences rotavirus virulence. The findings suggest that manipulating NSP4 could lead to new strategies to prevent or treat rotavirus infections. Fri, 17 Jan 2025 16:11:13 EST https://www.sciencedaily.com/releases/2025/01/250117161113.htm https://www.sciencedaily.com/releases/2025/01/250115124549.htm A research team reports on a novel observation of a plant protection mechanism in response to salt stress. The study opens new avenues of research to strengthen food security. Wed, 15 Jan 2025 12:45:49 EST https://www.sciencedaily.com/releases/2025/01/250115124549.htm https://www.sciencedaily.com/releases/2025/01/250114125129.htm Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting therapeutics with minimal side effects. Researchers have previously demonstrated antidepressant-like effects of delta opioid receptor agonists in rodents. In their latest study, they uncover the molecular and cellular mechanism underlying its action that can advance its therapeutic development. Tue, 14 Jan 2025 12:51:29 EST https://www.sciencedaily.com/releases/2025/01/250114125129.htm https://www.sciencedaily.com/releases/2025/01/250109141125.htm Researchers find cell migration doesn't only rely on generating force. A professor of mechanical engineering and materials science found that groups of cells moved faster with lower force when adhered to soft surfaces with aligned collagen fibers. Thu, 09 Jan 2025 14:11:25 EST https://www.sciencedaily.com/releases/2025/01/250109141125.htm https://www.sciencedaily.com/releases/2024/12/241218174849.htm Researchers are closer to understanding what drives the autoimmune disorder Sj gren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their latest study finds that impaired regulatory T cells are a critical contributing factor to Sj gren's disease in both mice and humans, and identifies an existing rheumatology drug as a promising therapy for the disease. Wed, 18 Dec 2024 17:48:49 EST https://www.sciencedaily.com/releases/2024/12/241218174849.htm https://www.sciencedaily.com/releases/2024/12/241213211320.htm Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective. Thus, finding ways to disarm that resistance and rejuvenate anti-cancer TILs so they can kill tumor cells is an important goal for cancer clinicians. Fri, 13 Dec 2024 21:13:20 EST https://www.sciencedaily.com/releases/2024/12/241213211320.htm https://www.sciencedaily.com/releases/2024/12/241209163205.htm Studying the cells of people and genetically engineered mice, scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are especially prone to developing aneurysms at the root of the aorta. Mon, 09 Dec 2024 16:32:05 EST https://www.sciencedaily.com/releases/2024/12/241209163205.htm https://www.sciencedaily.com/releases/2024/12/241202123451.htm Beta-blocker drugs -- commonly used to treat heart and blood pressure issues -- may slow the progression of Huntington's disease (HD), according to a new study. Mon, 02 Dec 2024 12:34:51 EST https://www.sciencedaily.com/releases/2024/12/241202123451.htm https://www.sciencedaily.com/releases/2024/11/241127135909.htm Factors beyond carbohydrates have a substantial influence on blood glucose levels meaning current automated insulin delivery systems miss vital information required for glucose regulation, a new study has found. Wed, 27 Nov 2024 13:59:09 EST https://www.sciencedaily.com/releases/2024/11/241127135909.htm https://www.sciencedaily.com/releases/2024/11/241127135510.htm Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Scientists have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of oxidative stress. Wed, 27 Nov 2024 13:55:10 EST https://www.sciencedaily.com/releases/2024/11/241127135510.htm https://www.sciencedaily.com/releases/2024/11/241127004149.htm A large new population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease -- aortic stenosis (AS). Wed, 27 Nov 2024 00:41:49 EST https://www.sciencedaily.com/releases/2024/11/241127004149.htm https://www.sciencedaily.com/releases/2024/11/241125195050.htm The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes. Mon, 25 Nov 2024 19:50:50 EST https://www.sciencedaily.com/releases/2024/11/241125195050.htm https://www.sciencedaily.com/releases/2024/11/241125163103.htm Researchers recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by specialized immune cells also tagged with a complementary but inert targeting molecule. Mon, 25 Nov 2024 16:31:03 EST https://www.sciencedaily.com/releases/2024/11/241125163103.htm https://www.sciencedaily.com/releases/2024/11/241125125218.htm In 2021, a research team discovered the insulin-inhibitory receptor 'Inceptor' and its role as a suppressor of the insulin signaling pathway. Now, the researchers have unlocked another, even more significant function of the receptor: it binds insulin and directs its breakdown within beta cells. This discovery could lead to new therapeutic approaches that not only strengthen beta cell function but also enable a causal treatment for diabetes. Mon, 25 Nov 2024 12:52:18 EST https://www.sciencedaily.com/releases/2024/11/241125125218.htm https://www.sciencedaily.com/releases/2024/11/241121115650.htm Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the door to better ways to manage high blood pressure and other vascular diseases. Thu, 21 Nov 2024 11:56:50 EST https://www.sciencedaily.com/releases/2024/11/241121115650.htm https://www.sciencedaily.com/releases/2024/11/241120121940.htm Researchers have led a clinical trial of a drug that mimics the effects of alcohol in more than 100 patients with laryngeal dystonia, a neurological condition that causes involuntary muscle spasms in the larynx and can have debilitating impacts on a person's voice. The trial was inspired by patient reports that their symptoms improved after consuming alcoholic beverages. Wed, 20 Nov 2024 12:19:40 EST https://www.sciencedaily.com/releases/2024/11/241120121940.htm https://www.sciencedaily.com/releases/2024/11/241118130050.htm When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals. This knowledge can be used to develop drugs for chronic pain that are more effective and have fewer side effects. Mon, 18 Nov 2024 13:00:50 EST https://www.sciencedaily.com/releases/2024/11/241118130050.htm https://www.sciencedaily.com/releases/2024/11/241114130159.htm Time spent sedentary beyond six hours per day during growth from childhood through young adulthood may cause an excess increase of 4 mmHg in systolic blood pressure, a new study shows. Continuously engaging in light physical activity (LPA) significantly mitigated the rise in blood pressure. Thu, 14 Nov 2024 13:01:59 EST https://www.sciencedaily.com/releases/2024/11/241114130159.htm https://www.sciencedaily.com/releases/2024/11/241112122737.htm Obesity causes insulin resistance by increasing activation of the sympathetic nervous system and the release of the stress hormone norepinephrine, according to a new study. Tue, 12 Nov 2024 12:27:37 EST https://www.sciencedaily.com/releases/2024/11/241112122737.htm https://www.sciencedaily.com/releases/2024/11/241111123249.htm All patients who have had a heart attack are typically treated using beta blockers. According to a recent study, this drug is unlikely to be needed for those heart patients who have a normal pumping ability. Now a sub-study shows that there is also a risk that these patients will become depressed by the treatment. Mon, 11 Nov 2024 12:32:49 EST https://www.sciencedaily.com/releases/2024/11/241111123249.htm https://www.sciencedaily.com/releases/2024/10/241017113538.htm The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications, especially GLP-1 agonists, can be used to treat obesity and diabetes in humans. Thu, 17 Oct 2024 11:35:38 EDT https://www.sciencedaily.com/releases/2024/10/241017113538.htm https://www.sciencedaily.com/releases/2024/10/241008122237.htm Researchers have now discovered that DNA sequence changes known to increase a person's risk for diabetes are linked to how well pancreatic cells can handle two different kinds of molecular stress. In people with these DNA changes, the insulin-producing cells in the pancreas may be more likely to fail or die when exposed to stress and inflammation. Tue, 08 Oct 2024 12:22:37 EDT https://www.sciencedaily.com/releases/2024/10/241008122237.htm