https://www.sciencedaily.com/news/health_medicine/bladder_cancer/ Bladder cancer. Read about the latest medical research on bladder cancer and related topics. en-us Tue, 08 Sep 2026 09:57:21 EDT Tue, 08 Sep 2026 09:57:21 EDT 60 https://www.sciencedaily.com/images/scidaily-logo-rss.png https://www.sciencedaily.com/news/health_medicine/bladder_cancer/ For more science news, visit ScienceDaily. https://www.sciencedaily.com/releases/2026/09/260904000326.htm Researchers have mapped breast tumors in striking detail and uncovered hidden pockets of dormant cancer cells that may help explain why cancer can return after treatment. Unlike rapidly dividing cells, these quiet cells can essentially hibernate, allowing them to evade chemotherapy and reactivate later. The team found that they are often surrounded by immune cells and connective tissue cells that may act like a protective shield. Sun, 06 Sep 2026 16:43:10 EDT https://www.sciencedaily.com/releases/2026/09/260904000326.htm https://www.sciencedaily.com/releases/2026/09/260904000324.htm Researchers have found a potential way to attack prostate cancers that evade treatment by changing their cellular identity. Combining two types of drugs reversed many of these changes and sharply slowed tumor growth in preclinical experiments, offering a possible new strategy for aggressive, treatment-resistant disease. Tue, 08 Sep 2026 06:46:38 EDT https://www.sciencedaily.com/releases/2026/09/260904000324.htm https://www.sciencedaily.com/releases/2026/08/260829235950.htm Researchers discovered a possible way cancer cells hide from the immune system: they build a thick, sugar-rich coating around themselves. High blood sugar can strengthen this protective shield under conditions that resemble the environment inside tumors, with the protein HSF1 playing a key role. Blocking this process could make cancer cells easier for the immune system to recognize and destroy. Mon, 31 Aug 2026 22:39:55 EDT https://www.sciencedaily.com/releases/2026/08/260829235950.htm https://www.sciencedaily.com/releases/2026/08/260826060617.htm Scientists created smart nanoparticles that can both illuminate hidden glioblastoma cells during surgery and destroy microscopic cancer left behind afterward. In mice, the treatment prevented recurrence and led to 100% survival at 60 days, though it has not yet been tested in humans. Thu, 27 Aug 2026 01:52:48 EDT https://www.sciencedaily.com/releases/2026/08/260826060617.htm https://www.sciencedaily.com/releases/2026/08/260824065546.htm Researchers have found a way to supercharge natural killer cells, powerful immune cells that can attack cancer, so they can penetrate solid tumors and keep fighting once inside. In mice, these specially prepared tissue-resident cells slowed the growth of several tumors, including melanoma and head and neck cancers, and worked even better when paired with the antibody drug cetuximab. Tue, 25 Aug 2026 08:56:22 EDT https://www.sciencedaily.com/releases/2026/08/260824065546.htm https://www.sciencedaily.com/releases/2026/08/260816044830.htm Engineered probiotic bacteria were able to infiltrate pancreatic tumors, stimulate cancer-fighting immune cells, and slow tumor growth in animal studies. Even more strikingly, the treatment worked better when combined with chemotherapy, radiation, or immunotherapy. Wed, 19 Aug 2026 08:10:13 EDT https://www.sciencedaily.com/releases/2026/08/260816044830.htm https://www.sciencedaily.com/releases/2026/08/260814011038.htm Researchers have uncovered a surprising way triple-negative breast cancer may turn the body against itself. Tumors appear to recruit macrophages—immune cells normally involved in healing and fighting infection—and use them to release a protein called BDNF that draws nerves into the tumor. Those nerves may then help the cancer grow, resist treatment, and potentially spread. Mon, 17 Aug 2026 08:06:50 EDT https://www.sciencedaily.com/releases/2026/08/260814011038.htm https://www.sciencedaily.com/releases/2026/08/260806050702.htm A protein that evolved long before the human circulatory system may help unlock stronger cancer treatments. When C3 is produced inside tumors, it blocks immune-suppressing cells and gives immunotherapy a better chance to work. Researchers were even able to recreate this effect in resistant tumors, significantly improving survival in mice. Sat, 08 Aug 2026 09:31:21 EDT https://www.sciencedaily.com/releases/2026/08/260806050702.htm https://www.sciencedaily.com/releases/2026/07/260731034204.htm Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes with small mistakes that allow new mutations to accumulate. Researchers believe this self-inflicted damage may help tumors evolve while also creating a potential target for new treatments. Sun, 02 Aug 2026 00:30:42 EDT https://www.sciencedaily.com/releases/2026/07/260731034204.htm https://www.sciencedaily.com/releases/2026/07/260727012123.htm A controlled mouse study has provided direct evidence that inherited genetics can steer how cancer begins and evolves after DNA damage. The discovery could eventually help doctors better predict cancer risk and tailor screening and treatments to each patient. Mon, 27 Jul 2026 04:29:41 EDT https://www.sciencedaily.com/releases/2026/07/260727012123.htm https://www.sciencedaily.com/releases/2026/07/260726015250.htm Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice and may offer hope for other hard-to-treat tumors. Sun, 26 Jul 2026 08:36:23 EDT https://www.sciencedaily.com/releases/2026/07/260726015250.htm https://www.sciencedaily.com/releases/2026/07/260716023607.htm Researchers are applying evolutionary theory to cancer by changing treatments before tumors have time to develop resistance. Mathematical models suggest that rapid, carefully timed switches between multiple therapies could improve cure rates. Wed, 22 Jul 2026 01:41:04 EDT https://www.sciencedaily.com/releases/2026/07/260716023607.htm https://www.sciencedaily.com/releases/2026/07/260715083542.htm A new experimental treatment may have found a way to outsmart glioblastoma’s toughest defense: the blood-brain barrier. Researchers used sugar-coated nanoparticles to ferry genetic instructions that restore a key tumor-suppressing protein directly into brain cancer cells. In mouse studies, the therapy increased median survival by 50% while shrinking tumors without noticeable damage to other organs. Thu, 16 Jul 2026 21:51:52 EDT https://www.sciencedaily.com/releases/2026/07/260715083542.htm https://www.sciencedaily.com/releases/2026/07/260714225525.htm An unusual leopard gecko that naturally develops aggressive tumors may become an important new model for cancer research. Scientists found its tumors share key genetic changes with human cancers, offering a rare opportunity to study the disease as it develops naturally. Tue, 14 Jul 2026 22:55:25 EDT https://www.sciencedaily.com/releases/2026/07/260714225525.htm https://www.sciencedaily.com/releases/2026/07/260709160655.htm A naturally occurring bacterium from amphibian intestines completely eliminated colorectal tumors in mice with a single treatment by both attacking cancer cells and activating the immune system. The findings point to a promising new type of cancer therapy that could one day work against many solid tumors. Fri, 10 Jul 2026 00:13:15 EDT https://www.sciencedaily.com/releases/2026/07/260709160655.htm https://www.sciencedaily.com/releases/2026/07/260708022212.htm Researchers found that mRNA cancer vaccines can recruit an unexpected immune cell to launch powerful tumor-fighting responses, overturning a long-held assumption about how the vaccines work. The discovery could lead to more effective cancer vaccines and help scientists tailor treatments for better patient outcomes. Thu, 09 Jul 2026 16:05:08 EDT https://www.sciencedaily.com/releases/2026/07/260708022212.htm https://www.sciencedaily.com/releases/2026/07/260708022158.htm Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the immune system in preclinical mouse studies. Combined with immunotherapy, the treatment produced complete remissions in multiple mice, raising hopes for a powerful new approach to prostate cancer. Wed, 08 Jul 2026 22:18:49 EDT https://www.sciencedaily.com/releases/2026/07/260708022158.htm https://www.sciencedaily.com/releases/2026/07/260701015237.htm Scientists have discovered that creatine may strengthen one of the immune system's most important cancer-fighting pathways by energizing dendritic cells that activate killer T cells. The promising results could eventually help make immunotherapy more effective, but they have not yet been tested in human patients. Wed, 08 Jul 2026 05:32:21 EDT https://www.sciencedaily.com/releases/2026/07/260701015237.htm https://www.sciencedaily.com/releases/2026/06/260626030430.htm A UCLA study has identified a hidden Achilles' heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors lacking the RB gene become critically dependent on the protein E2F3 for survival. Blocking E2F3 shut down tumor growth in laboratory models, and existing FDA-approved drugs may be able to exploit this vulnerability. The discovery could pave the way for faster development of more effective therapies. Sat, 04 Jul 2026 15:26:54 EDT https://www.sciencedaily.com/releases/2026/06/260626030430.htm https://www.sciencedaily.com/releases/2026/06/260623083119.htm Scientists at the University of Illinois Chicago have turned an unlikely source into a potential new weapon against cancer: bacteria that naturally live inside tumors. They developed a peptide called aurB, inspired by a bacterial protein, that infiltrates cancer cells and effectively cuts off their energy supply by targeting the mitochondria—the cells’ power plants. Tue, 07 Jul 2026 16:23:00 EDT https://www.sciencedaily.com/releases/2026/06/260623083119.htm https://www.sciencedaily.com/releases/2026/06/260623014014.htm Researchers found that a rare liver cancer evades immunotherapy by luring immune T cells away from the tumor and trapping them in nearby fibrous tissue. An FDA-approved drug called AMD3100 freed those T cells to attack the cancer, significantly improving the effectiveness of immunotherapy in tumor samples. Thu, 25 Jun 2026 10:38:45 EDT https://www.sciencedaily.com/releases/2026/06/260623014014.htm https://www.sciencedaily.com/releases/2026/06/260623014007.htm Scientists have identified a molecular switch that may help explain how colorectal cancer becomes deadly. When levels of a gene-regulating factor called GATA6 drop, cancer cells can shed their normal identity and transform into highly adaptable, fetal-like cells capable of spreading through the bloodstream and establishing new tumors in the liver. The study suggests that this dangerous transition is driven less by new genetic mutations and more by changes in how genes are switched on and off. Tue, 07 Jul 2026 04:36:40 EDT https://www.sciencedaily.com/releases/2026/06/260623014007.htm https://www.sciencedaily.com/releases/2026/06/260622091518.htm Researchers have identified a vitamin B12–based compound that can cross the blood-brain barrier and home in on glioblastoma tumors. In animal studies, the compound accumulated preferentially in tumor tissue and delivered sustained nitric oxide directly to cancer cells. It also worked synergistically with existing glioblastoma treatments, significantly enhancing their tumor-fighting effects. Sat, 27 Jun 2026 18:38:01 EDT https://www.sciencedaily.com/releases/2026/06/260622091518.htm https://www.sciencedaily.com/releases/2026/06/260622091512.htm Researchers tested experimental PCAI compounds against pancreatic cancer cells and found they had powerful anticancer effects. One leading compound blocked more than 90% of cancer cell migration, suggesting it could help prevent the spread of tumors. Rather than suppressing cancer signaling, the treatment hyperactivated key pathways until the cells essentially self-destructed. Mon, 29 Jun 2026 14:08:33 EDT https://www.sciencedaily.com/releases/2026/06/260622091512.htm https://www.sciencedaily.com/releases/2026/06/260619101349.htm Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting DNA it shouldn't, creating damage linked to cancer. Sat, 20 Jun 2026 08:27:35 EDT https://www.sciencedaily.com/releases/2026/06/260619101349.htm https://www.sciencedaily.com/releases/2026/06/260619020503.htm Some cancer cells evade treatment by entering a dormant state triggered by stress hormones. ETH Zurich scientists have created a light-controlled molecular switch that selectively destroys the receptors responsible for this survival mode. In laboratory lung cancer cells, the approach woke sleeping tumor cells and could help make future cancer therapies more effective while minimizing damage to healthy tissue. Sun, 05 Jul 2026 02:08:50 EDT https://www.sciencedaily.com/releases/2026/06/260619020503.htm https://www.sciencedaily.com/releases/2026/06/260602021641.htm A newly identified protein may be one of the biggest obstacles holding CAR T-cell therapy back. Researchers found that NFIL3 causes these engineered immune cells to become exhausted and lose their cancer-fighting power over time. When NFIL3 was disabled, the cells remained stronger for longer and controlled tumors more effectively in animal models. Tue, 02 Jun 2026 10:54:02 EDT https://www.sciencedaily.com/releases/2026/06/260602021641.htm https://www.sciencedaily.com/releases/2026/05/260523103943.htm Scientists have cracked open the “black box” of feline cancer in a landmark study that genetically analyzed nearly 500 cat tumors from around the world. The research uncovered striking similarities between cancers in cats, dogs, and humans — including shared cancer-driving genes tied to aggressive breast cancers. Sun, 24 May 2026 08:35:15 EDT https://www.sciencedaily.com/releases/2026/05/260523103943.htm https://www.sciencedaily.com/releases/2026/05/260515233329.htm Scientists have uncovered a surprising new trick used by one of cancer’s most notorious proteins. MYC, already infamous for fueling runaway tumor growth, also appears to help cancer cells survive by repairing their damaged DNA — including damage caused by chemotherapy and radiation. Researchers found that MYC can rush directly to broken DNA and recruit repair machinery, effectively helping tumors recover from treatments meant to destroy them. Sun, 17 May 2026 00:23:49 EDT https://www.sciencedaily.com/releases/2026/05/260515233329.htm https://www.sciencedaily.com/releases/2026/05/260509210646.htm Researchers found a new way to kill harmful “zombie” cells that linger after chemotherapy and help cancers become more aggressive. These senescent cells survive by relying on a protective protein called GPX4, even while sitting on the edge of a deadly iron-triggered collapse. New drugs remove that protection, causing the cells to self-destruct. In mice, the approach reduced tumor size and boosted survival, hinting at a promising new cancer therapy. Tue, 12 May 2026 21:22:09 EDT https://www.sciencedaily.com/releases/2026/05/260509210646.htm https://www.sciencedaily.com/releases/2026/04/260420014746.htm A key protein, HOXD13, helps melanoma tumors grow and evade the immune system by boosting blood supply and blocking cancer-fighting T cells. Disabling it shrinks tumors and reopens the door for the immune system—offering a new path for treatment. Tue, 21 Apr 2026 03:40:31 EDT https://www.sciencedaily.com/releases/2026/04/260420014746.htm https://www.sciencedaily.com/releases/2026/04/260411022031.htm Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools. The goal: more precise, personalized treatments that can outsmart even the most dangerous tumors. Sun, 12 Apr 2026 07:03:28 EDT https://www.sciencedaily.com/releases/2026/04/260411022031.htm https://www.sciencedaily.com/releases/2026/04/260405003933.htm Scientists in Canada have uncovered a surprising weakness in glioblastoma, one of the deadliest brain cancers. They found that certain brain cells—once believed to only support healthy nerves—can actually help tumors grow by sending signals that strengthen cancer cells. When researchers blocked this communication, tumor growth slowed dramatically in lab models. Sun, 05 Apr 2026 19:48:12 EDT https://www.sciencedaily.com/releases/2026/04/260405003933.htm https://www.sciencedaily.com/releases/2026/03/260326075550.htm Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release reservoirs that create uneven drug distribution. This means some cancer cells are heavily exposed while others are barely affected. Understanding this process could help doctors better tailor treatments and improve outcomes. Fri, 27 Mar 2026 08:31:17 EDT https://www.sciencedaily.com/releases/2026/03/260326075550.htm https://www.sciencedaily.com/releases/2026/03/260321012709.htm Researchers have discovered that cancer spread isn’t random—it follows a kind of biological “program.” By studying colon tumor cells, they identified gene patterns that signal whether a cancer is likely to metastasize. Their AI model, MangroveGS, can predict this risk with about 80% accuracy and even works across multiple cancer types. This could transform how doctors decide who needs aggressive treatment and who doesn’t. Sat, 21 Mar 2026 07:44:32 EDT https://www.sciencedaily.com/releases/2026/03/260321012709.htm https://www.sciencedaily.com/releases/2026/03/260321004445.htm Scientists have engineered probiotic bacteria to act as tumor-seeking drug factories. In mice, these bacteria infiltrated tumors and produced a cancer-fighting drug right where it was needed. This targeted approach could make treatments more effective and reduce side effects. More research is needed before it can be tested in people. Sat, 21 Mar 2026 01:26:09 EDT https://www.sciencedaily.com/releases/2026/03/260321004445.htm https://www.sciencedaily.com/releases/2026/03/260319044708.htm Scientists have found a way to make one of the most aggressive brain tumors vulnerable to the immune system. A single injection of a modified virus can invade glioblastoma, kill cancer cells, and summon immune fighters deep into the tumor. These immune cells persist and attack, which was linked to longer survival in patients. Fri, 20 Mar 2026 07:59:34 EDT https://www.sciencedaily.com/releases/2026/03/260319044708.htm https://www.sciencedaily.com/releases/2026/03/260318033143.htm Scientists have mapped the genetics of cancer in cats for the first time at scale, uncovering major overlaps with human cancers. Key mutations—like those linked to breast cancer—appear in both species, and some human cancer drugs may also work in cats. Because pets share our environments, these similarities could reveal shared causes of cancer. The research could lead to new treatments that benefit both animals and humans. Wed, 18 Mar 2026 19:12:17 EDT https://www.sciencedaily.com/releases/2026/03/260318033143.htm https://www.sciencedaily.com/releases/2026/03/260315225121.htm A redesigned cancer immunotherapy is showing striking early results after decades of disappointment with similar drugs. Researchers engineered a more powerful CD40 agonist antibody and changed how it’s delivered—injecting it directly into tumors instead of into the bloodstream. In a small clinical trial of 12 patients with metastatic cancers, six saw their tumors shrink and two experienced complete remission. Mon, 16 Mar 2026 20:18:42 EDT https://www.sciencedaily.com/releases/2026/03/260315225121.htm https://www.sciencedaily.com/releases/2026/03/260309225222.htm Colorblindness may be doing more than making traffic lights confusing — it could also be hiding a life-threatening warning sign. Researchers analyzing millions of medical records found that people with bladder cancer who are also colorblind have a 52% higher mortality rate over 20 years compared to those with normal vision. The likely reason: many people with color vision deficiency struggle to see red, making it harder to notice blood in urine, the most common early sign of bladder cancer. Tue, 10 Mar 2026 01:49:43 EDT https://www.sciencedaily.com/releases/2026/03/260309225222.htm https://www.sciencedaily.com/releases/2026/03/260305223240.htm A Rutgers-led study found that eating less protein may help slow liver cancer in people with impaired liver function. When damaged livers can’t properly clear toxic ammonia from protein metabolism, the excess ammonia can feed tumor growth. In mice, reducing dietary protein lowered ammonia levels, slowed tumor growth, and significantly improved survival. Fri, 06 Mar 2026 05:17:57 EST https://www.sciencedaily.com/releases/2026/03/260305223240.htm https://www.sciencedaily.com/releases/2026/03/260303050624.htm Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control. Tue, 03 Mar 2026 11:33:04 EST https://www.sciencedaily.com/releases/2026/03/260303050624.htm https://www.sciencedaily.com/releases/2026/02/260228093456.htm Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue. Sun, 01 Mar 2026 09:09:30 EST https://www.sciencedaily.com/releases/2026/02/260228093456.htm https://www.sciencedaily.com/releases/2026/02/260224023101.htm Researchers are engineering bacteria to invade tumors and consume them from the inside. Because tumor cores lack oxygen, they’re the perfect breeding ground for these microbes. The team added a genetic tweak that helps the bacteria survive longer near oxygen-exposed edges — but only once enough of them are present to trigger the change. It’s a carefully programmed biological attack that could one day offer a new way to destroy cancer. Tue, 24 Feb 2026 03:41:46 EST https://www.sciencedaily.com/releases/2026/02/260224023101.htm https://www.sciencedaily.com/releases/2026/02/260216084527.htm A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across dozens of tumor types. These molecules form unique molecular signatures that identify cancer type and subtype with remarkable accuracy. Some even drive tumor growth and metastasis. Because many are released into the bloodstream, a simple blood test can track how patients respond to treatment and predict survival. Tue, 17 Feb 2026 03:50:37 EST https://www.sciencedaily.com/releases/2026/02/260216084527.htm https://www.sciencedaily.com/releases/2026/02/260216044006.htm Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based nanovaccine, the team dramatically strengthened the immune system’s attack on HPV-driven tumors. One specific design slowed tumor growth, extended survival in animal models, and unleashed far more cancer-killing T cells than other versions made with the exact same components. Wed, 18 Feb 2026 10:00:32 EST https://www.sciencedaily.com/releases/2026/02/260216044006.htm https://www.sciencedaily.com/releases/2026/02/260212234216.htm Fish oil’s cancer-fighting reputation may hinge on a little-known gene. Researchers discovered that omega-3s like EPA and DHA help curb colorectal cancer only when the enzyme ALOX15 is present. Without it, fish oil sometimes increased tumor growth in mice—especially DHA. The results suggest that not all supplements work the same way, and genetics could determine who truly benefits. Fri, 13 Feb 2026 09:20:25 EST https://www.sciencedaily.com/releases/2026/02/260212234216.htm https://www.sciencedaily.com/releases/2026/02/260210040604.htm Scientists have uncovered a surprising way tumors turn the immune system to their advantage. Researchers at the University of Geneva found that neutrophils—normally frontline defenders against infection—can be reprogrammed inside tumors to fuel cancer growth instead. Once exposed to the tumor environment, these immune cells begin producing a molecule called CCL3 that actively promotes tumor progression. Tue, 10 Feb 2026 10:28:42 EST https://www.sciencedaily.com/releases/2026/02/260210040604.htm https://www.sciencedaily.com/releases/2026/02/260206012229.htm Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are packed with immune-suppressing regulatory T cells. New research finally explains why. Scientists discovered that these T cells aren’t all the same: one subtype actually helps keep tumors in check, while another shields cancer from immune attack. The balance between these “good” and “bad” cells can determine whether a tumor grows or shrinks. Fri, 06 Feb 2026 11:03:34 EST https://www.sciencedaily.com/releases/2026/02/260206012229.htm https://www.sciencedaily.com/releases/2026/02/260204121540.htm Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that some changes barely boost cancer signals, while others supercharge them. When matched against real patient data, the map accurately predicted cancer behavior across tissues. Thu, 05 Feb 2026 07:29:14 EST https://www.sciencedaily.com/releases/2026/02/260204121540.htm https://www.sciencedaily.com/releases/2026/01/260129080432.htm Researchers have discovered how pancreatic cancer reprograms its surroundings to spread quickly and stealthily. By using a protein called periostin, the tumor remodels nearby tissue and invades nerves, which helps cancer cells travel and form metastases. This process also creates a tough, fibrous barrier that makes treatments less effective. Targeting periostin could help stop this invasion before it starts. Fri, 30 Jan 2026 07:44:14 EST https://www.sciencedaily.com/releases/2026/01/260129080432.htm https://www.sciencedaily.com/releases/2026/01/260128075350.htm Scientists in South Korea have discovered that one of the most common malignant brain tumors in young adults may begin years before a tumor can be seen. IDH-mutant glioma, long treated by removing visible tumor tissue, actually starts when normal-looking brain cells quietly acquire a cancer-linked mutation and spread through the brain’s cortex. Using advanced genetic mapping and animal models, researchers traced the cancer’s true origin to glial progenitor cells that appear healthy at first. Wed, 28 Jan 2026 07:53:50 EST https://www.sciencedaily.com/releases/2026/01/260128075350.htm https://www.sciencedaily.com/releases/2026/01/260128075332.htm Scientists at Mount Sinai have unveiled a bold new way to fight metastatic cancer by turning the tumor’s own defenses against it. Instead of attacking cancer cells head-on, the experimental immunotherapy targets macrophages—immune cells that tumors hijack to shield themselves from attack. By eliminating or reprogramming these “bodyguards,” the treatment cracks open the tumor’s protective barrier and allows the immune system to flood in and destroy the cancer. Fri, 30 Jan 2026 01:05:29 EST https://www.sciencedaily.com/releases/2026/01/260128075332.htm https://www.sciencedaily.com/releases/2026/01/260127112137.htm Scientists at KAIST have found a way to turn a tumor’s own immune cells into powerful cancer fighters—right inside the body. Tumors are packed with macrophages, immune cells that should attack cancer but are usually silenced by the tumor environment. By injecting a specially designed drug directly into tumors, researchers were able to “reprogram” these dormant cells to recognize and destroy cancer. Wed, 28 Jan 2026 09:57:00 EST https://www.sciencedaily.com/releases/2026/01/260127112137.htm https://www.sciencedaily.com/releases/2026/01/260125083344.htm Cancer doesn’t evolve by pure chaos. Scientists have developed a powerful new method that reveals the hidden rules guiding how cancer cells gain and lose whole chromosomes—massive genetic shifts that help tumors grow, adapt, and survive treatment. By tracking thousands of individual cells over time, the approach shows which chromosome combinations give cancer an edge and why some tumors become especially resilient. Mon, 26 Jan 2026 04:41:20 EST https://www.sciencedaily.com/releases/2026/01/260125083344.htm https://www.sciencedaily.com/releases/2026/01/260124003811.htm Pancreatic cancer may evade the immune system using a clever molecular trick. Researchers found that the cancer-driving protein MYC also suppresses immune alarm signals, allowing tumors to grow unnoticed. When this immune-shielding ability was disabled in animal models, tumors rapidly collapsed. The findings point to a new way to expose cancer to the body’s own defenses without harming healthy cells. Sat, 24 Jan 2026 00:38:11 EST https://www.sciencedaily.com/releases/2026/01/260124003811.htm https://www.sciencedaily.com/releases/2026/01/260122074030.htm Researchers have identified a promising new weapon against triple-negative breast cancer, one of the most aggressive forms of the disease. An experimental antibody targets a protein that fuels tumor growth and shuts down immune defenses, effectively turning the immune system back on. In early tests, the treatment slowed tumor growth, reduced lung metastases, and destroyed chemotherapy-resistant cancer cells. Thu, 22 Jan 2026 23:43:30 EST https://www.sciencedaily.com/releases/2026/01/260122074030.htm https://www.sciencedaily.com/releases/2026/01/260120000323.htm Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies. Tue, 20 Jan 2026 00:03:23 EST https://www.sciencedaily.com/releases/2026/01/260120000323.htm https://www.sciencedaily.com/releases/2026/01/260115022808.htm A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening cancer vaccines. Scientists have now developed a drug that shuts down this pathway, dramatically boosting immune responses and slowing cancer growth in preclinical studies. Fri, 16 Jan 2026 06:06:55 EST https://www.sciencedaily.com/releases/2026/01/260115022808.htm https://www.sciencedaily.com/releases/2026/01/260114084129.htm Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials. Thu, 15 Jan 2026 02:10:05 EST https://www.sciencedaily.com/releases/2026/01/260114084129.htm